Introduction to the layering technique performed at Kkeuthan Clinic

Step 1: Pre-treatment preparation and skin cleansing

• If necessary, a cooling treatment or anesthetic cream is applied.

Kkeuthan Clinic's Skin Booster 4-Dimensional Layering Program

Step 2: 4th Skin Booster Layering (Utilizing MTS or Potenza RF treatment)

• First skin booster ampoule application

To induce a gentle reaction in the epidermal layer of the skin, the ampoule is applied thinly and evenly to perform the priming process.

• Second skin booster ampoule application

Targeting the epidermis and upper dermis, the ampoule is applied after light needling.

• Third skin booster ampoule application

Targeting the 'Deep Dermis', a crucial part that supports the skin, the needle depth is adjusted, and the ampoule is applied after needling.

• Fourth skin booster ampoule application

After intensively needling specific areas that the patient wishes to improve, such as deep pores, reduced elasticity, or firm scar borders, the ampoule is applied.

Step 3: Soothing management

• The treatment concludes with soothing care using a Jaungo modeling pack.

At Kkeuthan Clinic, a total of four layering techniques are applied in a single treatment session. This helps the skin booster ingredients to be absorbed evenly and sufficiently throughout the entire dermis. Kkeuthan Clinic's skin booster layering program is a treatment aimed at reducing possible discomforts such as bruising, swelling, incorrect injection, or hypersensitivity.

Kkeuthan Clinic's Treatment Method: Layering Technique

Due to its unique particle structure, Olidia Myo is difficult to absorb sufficiently through simple topical application. Therefore, Kkeuthan Clinic applies a skin booster layering absorption technique using MTS (Microneedle Therapy System) and needle radiofrequency (Potenza RF).

The average particle size of Olidia Myo is approximately 32㎲. This size allows it to be absorbed through the micro-channels created by MTS or Potenza RF. By utilizing a meticulous layering technique, we aim to reduce potential drug loss that can occur with topical application alone and ensure that the ingredients are delivered well into the deep dermis.

1) MTS Layering Technique

MTS creates fine channels for drug absorption in the skin. At Kkeuthan Clinic, layering is performed by precisely adjusting the MTS needle depth across four stages, focusing on enhancing ingredient absorption efficiency.

• Priming ampoule application on the epidermal layer

• Application targeting the epidermis to the upper dermis after light needling

• Intensive ampoule application to the deep dermis

• Ampoule application tailored to specific areas of concern such as reduced elasticity, deep scars, or enlarged pores

Afterward, the treatment is concluded with soothing care, such as a Jaungo modeling pack. This can help reduce discomfort and stabilize the skin.

2) Potenza RF Needle Radiofrequency Layering Technique

Potenza RF uses delicate micro-needles to create uniform absorption channels in the skin, followed by a brief application of radiofrequency thermal energy. During this process, the surrounding tissues of the channels coagulate and contract, which can help reduce fluid backflow (overflow) that might occur in typical needle procedures. This helps minimize drug loss and ensures that the Olidia Myo ingredients are well-delivered throughout the entire dermal layer.

Drug delivery can be more uniform than with manual injection methods. Especially when radiofrequency (RF) thermal energy and Olidia Myo (PLLA) are applied together, a synergistic effect of promoting collagen production both internally and externally can be expected. Similar to MTS treatment, needle depth adjustment is possible, and it proceeds with a 4-stage layering technique that reaches the deep dermis.

Kkeuthan Clinic's medical team carefully considers the patient's skin condition, degree of aging, and scar depth to select the appropriate method between MTS and Potenza RF, or to combine them for treatment.

Why does Kkeuthan Clinic perform treatments in this manner?

Olidia Myo is a high-concentration, high-molecular-weight PLLA powder. Therefore, it is crucial to fully hydrate it with saline at an appropriate ratio before treatment to stabilize its viscosity.

If this drug is injected intensively into one area using a typical injection (manual injection) method, or if there is an error in depth control, there is a possibility that the drug may clump together, forming hard nodules. Even if the hydration process is consistently performed, typical injection procedures may find it difficult to completely avoid the risk of nodule formation.

For these reasons, Kkeuthan Clinic has adopted a more cautious delivery method that enhances treatment efficacy while reducing the possibility of nodule side effects.

At Kkeuthan Clinic, we meticulously plan everything from the drug hydration process to specific viscosity control, micro-channel creation, and the 4-stage layering technique. This ensures that Olidia Myo particles are evenly and gradually dispersed within the tissue without clumping, inducing a smooth reaction. Enhancing treatment efficacy and reducing potential risks are key treatment principles at Kkeuthan Clinic.

About Olidia Myo Skin Booster

Olidia Myo is a collagen-inducing material based on pure PLLA (Poly-L-lactic acid), with mannitol and CMC working together. Targeting the deep dermis, deeper than typical skin boosters, it aims to go beyond simple skin surface improvement to aid in the regeneration of the supportive pillar (extracellular matrix, ECM) structure of the skin.

Main Ingredients of Olidia Myo (Total 121.7mg)

• Pure PLLA 50mg: A substance that helps generate autologous collagen and extracellular matrix (ECM)

• Mannitol 41.7mg: A substance that protects ingredients during freeze-drying and aids in antioxidant activity

The CMC 30mg component acts as a natural thickener. This can help maintain a stable viscosity during the procedure.

Why we use 'Amorphous PLLA' instead of 'Spherical' PLLA

Round and smooth spherical particles may have a slower absorption process upon contact with macrophages. In contrast, the amorphous particles in Olidia Mayo have a shape similar to well-polished pebbles. This form, thanks to its large surface area, helps macrophages attach more quickly.

The particle size is precisely engineered to reduce the possibility of cell damage from forcibly absorbing the particles. This induces the activation of M2 macrophages and promotes the secretion of TH2 cytokines. These signaling substances effectively stimulate fibroblasts in the skin, aiding in the synthesis of natural collagen and autologous tissue.

While existing PDLLA products (e.g., Juvelook) primarily act on the superficial layers of the skin, providing more delicate stimulation, Olidia Mayo can remain in the deeper dermis for longer, inducing a response that activates collagen production.

When to consider the procedure

1. Those concerned about decreased skin elasticity and reduced elasticity in the deeper dermal layer.

2. Those who have not achieved sufficient satisfaction with general skin boosters alone for improving pores or deep acne scars.

3. Those who desire natural improvement in skin density through their own collagen production, rather than artificial filler treatments.

4. Those concerned about fine lines along with decreased elasticity due to weakening of the skin's internal support structure (ECM).

5. Those who have expectations for the results of PLLA treatments but have felt burdened by the possibility of nodule formation or pain that can occur with injection procedures.

6. Those who expect tightening and lifting effects that improve firmness from deep within the skin.

Confirmation of Olidia Mayo's Clinical Evidence

The efficacy of Olidia Mayo's ingredients has been confirmed through various global studies and journal data.

• According to research published in Nature Materials on 'Physical approaches to biomaterial design,' particle shape and geometric structure influence macrophage responses. It was confirmed that amorphous structures with large surface areas can lead to efficient degradation processes within the body while reducing cellular stimulation.

• According to long-term clinical follow-up studies on PLLA, authentic PLLA components remain in body tissues for a relatively long period, from 9 months up to 24 months. This induces a gradual and consistent response, demonstrating the potential for more sustained collagen production (Long-term Effect) compared to PDLLA (DL-form).